IVF Diary Vol II: 15th Jan 16

Medication(s) administered and dosage(s). Gonal-F 300 iu & Menopur 150 iu.  Chris really is great at this injection thing.  I prepared the Gonal-F whilst Chris prepared the menopur.  We both read the instructions to remind us how to mix everything up, but like riding a bike, it was easy this time around.  Chris was a little bit nervous, but he needn’t have been, he did a great job.  I even looked down at the needle as he was injecting it – I am still not good at watching the needle break the skin though :-s.  The menopur did burn a bit as it went in, but it wasn’t quite as bad as I remember it to be.

ivf2_day1Stims

Medical procedures undertaken. Nil.

What are my symptoms? Period started right on cue yesterday morning!  Hot flashes and a bit of dizziness a couple of hours after my 2 first injections of this cycle.

How do I feel today?  A little bit annoyed that my plans to have a more relaxing stim period and 2WW are falling to pieces. Some short turn around-high impact work may fall on my plate next week.  I would have to forgo some of my steadfast principles for quality work and accept that in this case a 40% solution can only be delivered in the time lines given.  I have stuck to my guns though to some extent – where I was going to be taking the whole week off work, I am now only taking Monday and Friday off.  Tuesday and Thursday I will be working from home, Wednesday I’ll be in the office.  As we talked about this potential work, I started to feel sick to my stomach.  I started thinking back to last time around when I was trying to get my project finished and how stressed I was feeling about balancing the IVF process and work.  I let down my quality levels then – no one noticed (of course I noticed), in fact I got lots of praise for that piece of work.  Last week when a senior boss praised this work in front of the whole division I sat there quietly proud, but felt a bit sad that I had accomplished that with little help during a shitty time of IVF, followed by the whole ectopic pregnancy thing and ultimately miscarriage.  My boss has been great by not dumping everything on me right now, he quite easily could have done, but he didn’t so I appreciate that, but I can’t quite help  thinking about how IVF is holding me back from doing my absolute best.  I don’t think my colleagues around me think like that (fortunately they are all smart, intelligent people who know me), it is just myself I am fighting with these thoughts.

All that being said, I’ll talk about something positive.  We decided to go out for dinner at our local restaurant to celebrate surviving and nailing those first two injections.  Chris deserved his beer!  As we were finishing our meal the power went out in some of the building.  There was a storm that evening so it must have knocked the power out.  I said don’t worry, we are on a different power grid to our neighbours over the road (the block our restaurant was on) and last time their power went out, ours stayed on.  As we walked back, we realised that our grid was out and our neighbours’ over the road was on! Typical.  Fortunately we are well prepared for such events (for hurricanes and other storms etc), and carried on with the power of candles 🙂  It was a little bit romantic…I snuggled up in bed preparing for the power to be out all night and the temperature to dip.

power_out

Power outage = Candle lit bedroom!! Fortunately we have quite a few candelabras left over from our wedding table decorations still 😉

But then came the hot flashes!  I needn’t have worried about keeping warm, it seemed the drugs were doing a great job of that for me!!

Any results?  Estradiol <20 (as it should be, the same as IVF 1).  Progesterone <.2 (as it should be, the same as IVF 1). FSH 3.21 miU/ml (IVF 1 was 9.29, in 2014 it was 6.8) LH 0.771 miU/ml (IVF 1 was 3.48, in 2014 it was 4.9).  My LH level came up as red in my results…this means it was out of the ‘normal’ range, it is very low.  But not by much.  So I looked into it.  Although lower FSH is good, low LH is not good…apparently calculating the FSH-LH ratio and knowing the LH levels are good predictors of IVF outcome.  Let’s just say that I read several scientific reports, plugged in my numbers and the stats aren’t good.  But, the good news is that I don’t care! Why?  Because women with this kind of level and ratio still got pregnant.  And I am going to be one of those women in 4 weeks time 🙂 In your face science!!! **

What’s next? The same injections Sat, Sun, then monitoring appointment on Monday morning.

Weight. Work stress = nom nom nom bads.  But I did do the mixed martial arts P90x3 routine and pushed myself hard, so I don’t feel so bad.

Waist.  NSTR

Boobs. NSTR

Hours of Sunshine 🙂 Still NONE.  Let’s see if the sun comes out this weekend!

Fun Activity to keep Dani from going insane. IT’S FRIIIIIIIIDAYYYYYYY!!  I need say no more.  Surprise date night.

*Notes.  I take First Response Reproductive Health multi vitamin gummies (pre-natal) and CoQ10 200mg gummies daily.  NSTR = Nothing Significant To Report.

** Reserve right to have science egg in my face later

Funny conversations you probably only have when suffering infertility #1

confusingThere are probably a few conversations we will only ever have as a direct result of suffering from infertility.  This particular conversation ended up to be completely random as I feel more comfortable talking about my period with my husband now, so here is how it went….

(Scene – In car on way home from Softball game)

Dani (nonchalantly and randomly not expecting a response from Chris) : “I hate my period, why does my period have to be so sucky?”

Chris: “Does your retroverted uterus effect your period?  If it wasn’t upside down, would that mean your period will happen faster?”

Dani: “Hmmmm well I already suffer from twice as much blood as the daily average, but in half the amount of time, so I don’t think gravity has much of an impact on my blood flow!  But it is a good point…I wonder if gravity impacts periods and whether an upside down uterus means that blood has to be squeezed out rather than gravitationally slowly falling out as it de-lines.  Is this potentially why my period is twice as heavy each day but over and done with in 2 or 3 days?”

Dani picks up iPhone and asks Siri: “Does gravity affect menses?”

Siri replies with several websites, mostly focusing on women in space travel.  It is FASCINATING!!!! So what do you think?  How does a woman have a period in space?

Here is an article from www.thestraightdope.com that fully answered our question and more…EVERY DAY IS A SCHOOL DAY!!!!!

Dear Cecil:

Without gravity, how do female astronauts menstruate while in space?

Cecil replies:

For a while there, Gayle, the question wasn’t how women would menstruate in space but whether it was too risky to find out.

Although the first female cosmonaut, Valentina Tereshkova, had flown inVostok 6 in 1963, women were excluded from the U.S. space program during its early years. The official reason for this was that, as a matter of policy, U.S. astronauts were drawn from the ranks of military test pilots, and all the test pilots were men. If you ask me, though, the real reason was American male panic about women and their mysterious inner workings. Several plane crashes in the 1930s had involved menstruating female pilots, and experts — male experts, of course — suggested that putting a woman with “menstrual disturbances” in the cockpit was an invitation to disaster. Eventually the more hysterical fears receded, but some space medics still harbored serious concerns about menstruation when NASA began planning to put women in space in the 1970s.

From a certain point of view, I suppose, these concerns weren’t completely crazy. When a woman has her period, normally the menstrual flow is forcibly expelled from the cervix. However, given the low-gravity environment of space, some scientists wondered about the possibility of “retrograde menstruation,” the backward flow of menstrual blood up into the fallopian tubes. This occurs sometimes on earth and is thought to lead to endometriosis, a disorder in which tissue that normally lines the uterus grows where it shouldn’t. Prior to the 1983 space shuttle flight by Sally Ride, the first U.S. woman to exit our atmosphere, consultants told NASA that female astronauts should take hormones to manage their menstrual cycles to reduce flow volume and ideally avoid having a period while in space.

Unsurprisingly, to women anyway, most of the anticipated problems never materialized. There’s no evidence retrograde menstruation occurs in space, and even if it did, it probably wouldn’t cause endometriosis: reverse flow seems to trigger this condition only in those who experience it chronically. Returning women astronauts who’ve menstruated in space report that everything worked the way it usually does. The mechanics of a zero-G period haven’t been fully explicated in the scientific literature, but according toPrinciples of Clinical Medicine for Space Flight (2008), astronauts have “access to multiple sanitary products for menstruation, including pads, mini-pads, and tampons in plain and deodorant versions,” and presumably capillary attraction accomplishes what the lack of gravity can’t. (We might have predicted as much, since bedridden women usually menstruate OK.) Incidentally, for times when going to the bathroom is impossible for an extended period, such as launches, spacewalks, and landings, “crewmembers of both sexes have available a maximum absorbency garment (MAG) that can retain up to 2000 ml of urine, blood, or feces.” Not your ideal working conditions, but a small sacrifice to make for the world’s coolest job.

Female astronauts do face some challenges in space. Internal medicine specialist and space buff William Rowe notes that women are more likely to develop decompression sickness during their periods. That’s a problem mostly during space walks, so he suggests any excursion by a woman be timed for a different part of her cycle. Before you peg Rowe as a chauvinist scumbucket, note that he also thinks women are, on the whole, better suited than men to a low-gravity environment. In a 2004 article in the Journal of Men’s Health and Gender, he argues that for long-term space exploration an all-female crew might be the best bet. His reasons:

(1) Menstruation rids the body of iron. That’s a good thing, because space flight can reduce one’s production of a protein that normally sops up excess iron, and “increased free iron can be extremely toxic.”

(2) Women produce a lot more estrogen than men, and they also have lower epinephrine levels. For reasons we needn’t get into, these factors reduce the likelihood of heart attacks and other cardiovascular problems while in space.

(3) Some of the Apollo 15 astronauts experienced pain and swelling of their fingertips while on the surface of the moon. Rowe hypothesizes that this is less likely to happen to women because “estrogen reduces vascular smooth muscle tone.”

It might also be pointed out that women on average take up less room in cramped spacecraft cabins, consume fewer resources, and are more inclined to ask for directions when lost. Finally, to be blunt, who would you rather have up there: female astronauts who, worst case, are hormonally challenged on a fairly predictable schedule once a month, or male astronauts subject to random testosterone attacks any time at all?